The market for hepatic encephalopathy was estimated to be around USD 400 million in 2021 and is expected to grow at a compound annual growth rate (CAGR) of 5.5% to reach approximately USD 600 million in 2030.
Hepatic Encephalopathy is a type of brain condition that occurs in some people who have liver disease. HE manifests as a range of neuropsychiatric symptoms ranging from minor fluctuating cognitive impairment to coma, and it is a substantial contributor to morbidity in liver disease patients. It is seen in acute liver failure, liver bypass surgeries (such as shunt surgery and trans-jugular intrahepatic portosystemic shunt), and cirrhosis, and is categorized as Types A, B, and C HE.
Furthermore, Hepatic Encephalopathy can be linked with more serious symptoms such as decreased alertness, shortened attention span, abnormalities in sleep patterns, moderate disorientation, a decreasing capacity to complete mental activities, and mood or personality changes. Changes in memory, focus, and intellectual function may be more obvious than in mild hepatic encephalopathy (MHE).
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Hepatic Encephalopathy Market Segmentation
By Distribution Channel
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
Key Company
Mallinckrodt Pharmaceuticals, Lupin, Salix Pharmaceuticals, Umecrine Cognition AB, Norgine B.V., Ferring B.V., Pfizer Inc., Bausch Health Companies, Inc., Takeda Pharmaceutical Company Limited, GlaxoSmithKline plc., Merck & Co., Inc., Johnson & Johnson Services, Inc., Hikma Pharmaceuticals PLC, ASKA Pharmaceutical Co., Ltd., Amgen Inc., AbbVie Inc., and others are among the key companies operating in the global hepatic encephalopathy market.
Hepatic Encephalopathy Market Outlook
The management of OHE comprises treating individuals with acute Hepatic Encephalopathy episodes, avoiding Hepatic Encephalopathy recurrence, and identifying and controlling triggering factors linked with Hepatic Encephalopathy development. Non-absorbable disaccharides (lactitol and lactulose) and non-absorbable antibiotics (Rifaximin) are the two main types of medicinal treatment for hepatic encephalopathy. The hyperammonemia and inflammation caused by urea breakdown in cirrhosis have prompted the development of Hepatic Encephalopathy medicines that target gut bacteria. The US FDA has authorized therapies for OHE, however, there are also some unapproved medicines accessible. It is crucial to remember that in individuals with cirrhosis and portosystemic shunting, skeletal muscle mass, and renal clearance are critical for neurotoxic clearance.
Scope of the Report
- The Hepatic Encephalopathy market research study provides a detailed review of the disease, including its etiology, signs and symptoms, pathophysiology, genetic foundation, and current treatment options.
- The epidemiology and therapy of Hepatic Encephalopathy have been well investigated.
- Furthermore, an extensive overview of both present and emerging therapeutics for Hepatic Encephalopathy is offered, as well as an appraisal of future medicines that will influence the current treatment landscape.
- The research includes a full evaluation of the Hepatic Encephalopathy market, both historical and anticipated, as well as the 7MM medication outreach program.
- The patient-based Hepatic Encephalopathy market forecasting research gives you an advantage when building business strategies by identifying trends that shape and drive the 7MM Hepatic Encephalopathy market.
Region Insights
North America is expected to have the highest revenue share over the projection period. The region’s early adoption of breakthrough technologies, rising frequency of liver disorders, and expanding research and development capabilities all contribute to the region’s growing market share. According to the National Center for Biotechnology Information (NCBI), almost 7-11 million instances of hepatic encephalopathy were reported in the United States in September 2020, with around 150,000 additional diagnoses per year. Approximately 20% of newly diagnosed patients have liver cirrhosis, and over 60% have chronic hepatitis C, either alone or in combination with alcohol-related liver disease. Furthermore, around 70% of people with liver cirrhosis show signs of hepatic encephalopathy.
The regional market has benefited from increased healthcare spending and infrastructure construction, as well as a favorable regulatory environment. Furthermore, increased community knowledge of liver disease and cancer has boosted area income. Furthermore, the presence of key market participants benefits the region by allowing for innovative treatment replacements. These factors are projected to boost revenue growth in the area throughout the projection period.
Asia Pacific is expected to expand at the fastest CAGR throughout the projection period. This is due to higher healthcare infrastructure building costs, an increase in neurological ailments, and increased research and development activities for the diagnosis and treatment of liver diseases. Furthermore, alcohol consumption is highest in the Asia Pacific area, which includes highly urbanized nations and territories. This results in a large number of people with liver problems, accelerating the demand for suitable treatment. All of these variables are expected to assist the region’s revenue growth throughout the projection period.
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