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What is the projected market size of the liquid chromatography devices industry, and what is its expected CAGR?
The liquid chromatography devices market size has grown strongly in recent years. It will grow from $4.39 billion in 2024 to $4.64 billion in 2025 at a compound annual growth rate (CAGR) of 5.9%. The growth in the historic period can be attributed to the rise of biologics and biosimilars, increasing concerns over food safety and contamination, forensic and toxicology applications, expansion of academic research in life sciences, and the growing generic drug.
The liquid chromatography devices market size is expected to see strong growth in the next few years. It will grow to $5.77 billion in 2029 at a compound annual growth rate (CAGR) of 5.6%. The growth in the forecast period can be attributed to rising demand in pharmaceutical and biotech industries, the growing focus on personalized medicine, regulatory compliance, and quality control in manufacturing, increasing demand for analytical instruments, and a surge in biopharmaceutical production. Major trends in the forecast period include automation and AI in chromatography, automation and robotics integration, miniaturization and portability of systems, cloud-enabled chromatography data systems (CDS), and advancements in column technologies.
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What external factors are influencing the liquid chromatography devices market’s growth momentum?
The rise in biosimilar products is expected to propel the growth of the liquid chromatography devices market going forward. Biosimilar products refer to biologic medical products that are highly similar to an already approved reference product, with no clinically meaningful differences in terms of safety, effectiveness, and quality. The rise in biosimilar products is due to the increasing demand for cost-effective alternatives to expensive biologic drugs as patents for many original biologics expire, allowing more manufacturers to develop and market similar versions with comparable efficacy and safety. Liquid chromatography devices support the development and quality assurance of biosimilar products by enabling precise separation, identification, and quantification of complex biological molecules to ensure structural and functional similarity to reference biologics. ?For instance, in January 2023, according to Cardinal Health Inc., a U.S.-based healthcare company, the U.S. had 33 FDA-approved biosimilar products as of January 2022, with 21 available on the market. By 2023, this number had increased to 40 FDA-approved biosimilars, with 25 commercially available, demonstrating significant growth in both approvals and market availability. Therefore, the rise in biosimilar products is driving the growth of the liquid chromatography devices market.
What are the major market segments driving the growth of the liquid chromatography devices industry?
The liquid chromatography devices market covered in this report is segmented –
1) By Type: High-Performance Liquid Chromatography (HPLC), Ultra-High-Performance Liquid Chromatography (UHPLC), Low-Pressure Liquid Chromatography (LPLC), Other Types
2) By Accessories: Columns, Auto-Sampler Accessories, Other Accessories
3) By Application: Pharmaceutical And Biotechnology, Food And Beverage, Environmental Testing, Clinical Research, Other Applications
Subsegments:
1) By High-Performance Liquid Chromatography (HPLC): Analytical High-Performance Liquid Chromatography, Preparative High-Performance Liquid Chromatography, Reverse Phase High-Performance Liquid Chromatography, Normal Phase High-Performance Liquid Chromatography, Ion Exchange High-Performance Liquid Chromatography, Size Exclusion High-Performance Liquid Chromatography
2) By Ultra-High-Performance Liquid Chromatography (UHPLC): Reverse Phase Ultra-High-Performance Liquid Chromatography, Normal Phase Ultra-High-Performance Liquid Chromatography, Ion Exchange Ultra-High-Performance Liquid Chromatography, Hydrophilic Interaction Ultra-High-Performance Liquid Chromatography (HILIC), Supercritical Fluid Ultra-High-Performance Liquid Chromatography
3) By Low-Pressure Liquid Chromatography (LPLC): Isocratic Low-Pressure Liquid Chromatography, Gradient Low-Pressure Liquid Chromatography, Affinity Low-Pressure Liquid Chromatography, Gel Filtration Low-Pressure Liquid Chromatography, Ion Exchange Low-Pressure Liquid Chromatography
4) By Other Types: Flash Chromatography, Simulated Moving Bed Chromatography, Chiral Chromatography, Displacement Chromatography
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#What are the top market trends driving innovation in the liquid chromatography devices industry?
Major companies operating in the liquid chromatography devices market are focusing on developing technologically advanced products, such as next-generation high-performance liquid chromatography (HPLC) systems, to improve throughput, accuracy, and operational efficiency. A next-generation HPLC system is an advanced analytical instrument designed to provide faster separations, higher sensitivity, and improved data reproducibility, optimizing laboratory workflows and enhancing analytical precision. For instance, in October 2024, Agilent Technologies, a US-based biotechnology research company, introduced the Agilent InfinityLab LC Series, a next-generation line of high-performance liquid chromatography (HPLC) systems. This innovative platform redefines performance and usability by offering faster analysis, reduced solvent usage, and enhanced system intelligence. By integrating real-time system diagnostics and advanced automation features, the InfinityLab LC Series simplifies complex workflows, boosts laboratory productivity, and ensures consistent results.
Who are the key market players contributing to the growth of the liquid chromatography devices industry?
Major companies operating in the liquid chromatography devices market are Hitachi High-Tech Corporation, General Electric Company, Thermo Fisher Scientific Inc., Merck KGaA, Sartorius AG, PerkinElmer Inc., Tosoh Bioscience Inc., Shimadzu Corporation, Revvity Inc., Waters Corporation, Bio-Rad Laboratories Inc., Hamilton Company, Phenomenex Inc., Gilson Incorporated, Trajan Scientific, Restek Corporation, Showa Denko K.K, SCION Instruments Ltd., SIELC Technologies, JASCO Inc.
Which regions are leading the growth of the liquid chromatography devices market globally?
North America was the largest region in the liquid chromatography devices market in 2024. The regions covered in the liquid chromatography devices market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
How Can Companies Use The Liquid Chromatography Devices Market Report to Drive Business Results?
This report provides actionable insights tailored for business use—not academic analysis. Companies can leverage the data to:
• Time market entry or expansion using growth forecasts and CAGR trends.
• Develop competitive products by tracking key technology shifts and user preferences.
• Tailor regional strategies with in-depth geographic data and local market dynamics.
• Benchmark and plan partnerships using competitive landscape insights.
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