The CAR-T Therapy Global Market Report 2020-30 by The Business Research Company describes and explains the global CAR-T therapy market and covers 2015 to 2020, termed the historic period, and 2020 to 2025, termed the forecast period, along with further forecasts for the period 2025-2030. The report evaluates the market across each region and for the major economies within each region.
The CAR-T Therapy Global Market Opportunities And Strategies Report covers CAR-T therapy market drivers, CAR-T therapy market trends, CAR-T therapy market segments, CAR-T therapy market growth rate, CAR-T therapy market major players, and CAR-T therapy market size.
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The CAR-T therapy market report focuses particularly on identifying the trends, opportunities, and strategies that can lead to success. O&S reports are available off the shelf and can be delivered to clients on the day of purchase.
CAR-T Therapy Global Market Opportunities And Strategies Report is the most comprehensive report available on this market and will help gain a truly global perspective as it covers 60 geographies. The chapter on the impact of COVID-19 gives valuable insights on supply chain disruptions, logistical challenges, and other economic implications of the virus on the market. The chapter also covers markets which have been positively affected by the pandemic.
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Trends in the market include:
Remodeled CAR-T Cell Therapy for Fewer Side Effects-
The developers and providers of the CAR-T therapy market are investing in research and development to remodel the design of CAR-T therapy to reduce its side effects on cancer patients. The original CAR-T therapy causes neurologic side effects such as delirium, speech problems, seizures and tremors though it provides long-lasting remissions for some patients with very advanced cancer. The remodeled CAR-T therapy with a renewed design results in far fewer neurologic side effects than that of the original therapy. It also helps to reduce the levels of cytokines which cause neurologic side effects. For instance, in February 2020, the National Cancer Institute in the United States modified the design of the original CAR-T therapy and conducted it on 20 patients as trial. The results showed that only one patient out of the 20 in the trial had severe neurologic side effects. The new CAR-T therapy also resulted in the slow growth of tumors and minimized the levels of cytokines.
Off-The-Shelf Allogeneic CAR-T Therapy for Improved Treatment-
Companies in the CAR-T therapy market are focusing on developing off-the-shelf allogeneic CAR-T therapy for new and improved cancer treatment. The use of the first type of allogeneic CAR-T therapy has many benefits including decreased cost using an industrialized process, time for multiple cell modifications, immediate availability of cryopreserved batches for patient treatment, redosing or combination of CAR-T cells directed against different targets and possible standardization of the CAR-T cell product. However, this therapy may cause life-threatening graft-versus-host disease and may quickly destroy the allogeneic CAR-T cells by the host immune system. The new-generation allogeneic CAR-T therapy helps to overcome these challenges. For instance, in November 2019, Precision Biosciences, Inc., a biotechnology company created a new generation allogeneic CAR-T therapy and is conducting an ongoing? Trial of this therapy by creating its first off-the-shelf allogeneic CAR-T therapy candidate known as PBCAR0191. This is? In collaboration with Servicer, an international pharmaceutical company and is mainly for the patients in need of advanced cancer treatment options.
The market is segmented:
By Target Antigen-
a. CD19 Therapy
b. CD22 Therapy
c. BCMA Therapy
d. Others
By Application-
a. Acute Lymphoblastic Leukemia
b. Diffuse Large B-Cell Lymphoma
c. Follicular Lymphoma
d. Chronic Lymphocytic Leukemia
e. Multiple Myeloma
f. Others
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