Overview and Scope
Biobetters refer to biologic drugs that are similar to existing biologics but have been enhanced to offer improved efficacy, safety, or other clinical benefits. These improvements can include better dosing regimens, reduced side effects, increased stability, or more convenient administration methods, providing a competitive advantage over the original biologics.
Sizing and Forecast
The biobetters market size has grown rapidly in recent years. It will grow from $60.73 billion in 2023 to $67.81 billion in 2024 at a compound annual growth rate (CAGR) of 11.7%. The growth in the historic period can be attributed to increased understanding of disease mechanisms, growing healthcare expenditure, enhanced manufacturing technologies, technological innovations in drug delivery, advancements in protein engineering, increased demand for improved therapeutic efficacy.
The biobetters market size is expected to see rapid growth in the next few years. It will grow to $105.94 billion in 2028 at a compound annual growth rate (CAGR) of 11.8%. The growth in the forecast period can be attributed to advancements in biotechnology, growing emphasis on personalized medicine, expanding pipelines of biopharmaceutical companies, rising prevalence of chronic diseases, favorable regulatory landscapes, heightened investments in research and development, advance healthcare infrastructure. Major trends in the forecast period include development of novel biobetters , protein engineering and rational design, focus on therapeutic areas, advanced healthcare infrastructure, development of next-generation sequencing (NGS) technologies ,advances in high-throughput screening (HTS) technologies.
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Segmentation & Regional Insights
The biobetters market covered in this report is segmented –
1) By Drug Class: Erythropoietin Biobetters, Granulocyte-Colony Stimulating Factor (G-CSF) Bioreactors, Interferon Biobetters, Insulin Biobetters, Monoclonal Antibodies Biobetters, Antihemophilic Factors, Other Drug Classes
2) By Route of Administration: Oral, Subcutaneous, Inhaled, Intravenous, Other Routes
3) By Disease Indication: Diabetes, Cancer, Renal Disease, Neurodegenerative Diseases, Genetic Disorder-Hemophilia, Other Diseases
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
North America was the largest region in the biobetters market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the biobetters market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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Major Driver Impacting Market Growth
The rising incidence of chronic kidney diseases is expected to propel the growth of the biobetters market going forward. Chronic kidney disease (CKD) is defined as a long-term illness that causes the kidneys to malfunction and eventually stop functioning. The prevalence of chronic kidney disease (CKD) is increasing due to aging demographics, elevated incidences of diabetes and hypertension, poor dietary habits, sedentary lifestyles, environmental pollution, and enhanced diagnostic capabilities. Biobetters help in the management of chronic kidney disease (CKD) by offering enhanced efficacy, reduced side effects, better dosing regimens, and improved stability compared to original biologic treatments, leading to better patient outcomes. For instance, according to the Australian Institute of Health and Welfare (AIHW), an Australia-based government agency for public health, in 2021, approximately 20,000 fatalities in Australia were linked to chronic kidney disease, accounting for 12% of the total mortality rate in 2021. Therefore, the rising incidence of chronic kidney diseases is driving the growth of the biobetters market.
Impact Of Autoimmune Diseases On The Biobetters Market
The increasing prevalence of autoimmune diseases is expected to propel the growth of the biobetters market going forward. Autoimmune diseases are disorders that occur when an organism’s immune system unintentionally attacks healthy cells. Autoimmune diseases are increasing due to various factors, including genetic predisposition, environmental influences, and lifestyle changes. Biobetters help in autoimmune disorders by providing enhanced efficacy, reduced side effects, improved dosing regimens, and increased stability compared to original biologic treatments, leading to more effective and tolerable management of these conditions. For instance, in December 2023, according to the Australian Institute of Health and Welfare (AIHW), an Australia-based government agency for public health, rheumatoid arthritis comprised 2.0% of the total disease burden in 2023. In 2021, it led to 1,145 deaths, equivalent to 3.2 deaths per 100,000 people, accounting for 0.7% of all fatalities. Therefore, the increasing prevalence of auto-immune diseases is driving the growth of the biobetters market.
Key Industry Players
Major companies operating in the biobetters market are Pfizer Inc., Johnson & Johnson, Merck & Co Inc., AbbVie Inc., Bayer AG, Sanofi Aventis LLC, Bristol-Myers Squibb Company, Novartis AG, GlaxoSmithKline plc, F Hoffmann La Roche Ltd., Eli Lilly and Co Ltd., Gilead Sciences Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., Regeneron Pharmaceuticals Inc, CSL Behring GmbH, Biogen Inc., GRIFOLS USA LLC, Celltrion Inc., Lonza Group AG, Ionis Pharmaceuticals Inc., Incyte Corporation, Amicus Therapeutics Inc., Genentech Inc., Sun Pharmaceutical Industries
The biobetters market report table of contents includes:
1. Executive Summary
- Biobetters Market Characteristics
- Biobetters Market Trends And Strategies
- Biobetters Market – Macro Economic Scenario
- Global Biobetters Market Size and Growth
…..
- Global Biobetters Market Competitive Benchmarking
- Global Biobetters Market Competitive Dashboard
- Key Mergers And Acquisitions In The Biobetters Market
- Biobetters Market Future Outlook and Potential Analysis
- Appendix
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