G-Protein Coupled Receptors (GPCRs) Market Overview
The G-Protein Coupled Receptors (GPCRs) market, valued at $3.44 billion in 2023, is projected to reach $5.42 billion by 2030, growing at a CAGR of 6.7%. GPCRs, also known as seven-pass transmembrane receptors, are vital components in drug discovery due to their role in signal transmission and binding external molecules to intracellular responses.
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Market Dynamics
Cancer Research Fuels Market Growth
The rising prevalence of cancer and lifestyle diseases such as cardiovascular and respiratory conditions is a key driver of the GPCRs market. In 2023, approximately 700 GPCR-targeted drugs were approved globally, further emphasizing the critical role these receptors play in modern medicine.
Advances in Drug Discovery Techniques
Breakthroughs in computational methods for receptor structure design are simplifying drug development. Collaboration among global institutions like the University of Southern California and Moscow Institute of Physics and Technology has resulted in innovative thermally stable GPCRs for drug formulation.
Challenges
The high cost of GPCR cell lines and a shortage of skilled professionals in developing regions remain significant barriers. Moreover, unfavorable reimbursement policies in some markets may impact growth.
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Regional Insights
North America Leads the Market
North America dominated the GPCRs market in 2023, thanks to strategic investments in cancer research, approval of GPCR-targeted therapies, and robust drug discovery activities. In November 2021, 134 GPCR targets were approved for drugs in the US and Europe.
Asia-Pacific Emerges as a Growth Hotspot
The APAC region is anticipated to witness the fastest growth due to government investments in biotechnology, rising per capita income, and increased focus on biopharmaceuticals in countries like Vietnam, Thailand, and South Korea. Key players such as Sosei Heptares and NB Health Laboratory are driving regional advancements.
Europe
European countries, led by Germany, France, and the UK, continue to play a pivotal role in innovative drug discovery, with key mergers and acquisitions strengthening their foothold in the GPCR market.
Key Developments in Mergers and Acquisitions
Thermo Fisher Scientific’s Expansion in Asia
Thermo Fisher has announced strategic partnerships with biopharma companies in Japan and Singapore, focusing on GPCR-targeted drug assays.
Sosei Heptares in Japan
Sosei Heptares has entered into collaborations with European biotech firms to advance allosteric modulator research for GPCRs.
South Korea’s WuXi AppTec
WuXi AppTec recently acquired a US-based drug discovery startup, enhancing its capabilities in GPCR-targeted drug development.
Arena Pharmaceuticals Acquisition by Pfizer
Pfizer’s acquisition of Arena Pharmaceuticals has bolstered the company’s GPCR drug portfolio, particularly in oncology.
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G-Protein Coupled Receptors (GPCRs) Market Segmentation
by Product
Cell Lines
Detection Kits
Cell Culture Reagents
Ligands
by Assay Type
cAMP Functional Assays
Calcium Functional Assays
β-Arrestin Functional Assays
Radioligand Binding and GTPγS Functional Assays
Internalization Assays
Trafficking Assays
Other Assays
by Application
Cancer Research
CNS Research
Metabolic Research
Cardiovascular Research
Respiratory Research
Inflammation Research
Other Application
G-Protein Coupled Receptors (GPCRs) Market Key Players
Thermo Fisher Scientific, Inc.
Becton, and Dickinson and Company
Abcam plc.
Enzo Life Sciences, Inc.
Promega Corporation.
PerkinElmer Inc.
QIAGEN
Merck KGaA
HD Biosciences Co., Ltd
Cisbio Bioassays
Eurofins DiscoverX Products.
Actelion Pharmaceuticals Ltd
Accure Pharma
Anchor Therapeutics.
Arena Pharmaceuticals, Inc.
ADDEX THERAPEUTICS
WuXi AppTec
BioInvenu, Inc.
Molecular Devices, LLC.
Corning Incorporated
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Key questions answered in the G-Protein Coupled Receptors (GPCRs) Market are:
- What growth strategies are the players considering to increase their presence in G-Protein Coupled Receptors (GPCRs) ?
- What are the upcoming industry applications and trends for the G-Protein Coupled Receptors (GPCRs) Market?
- What segments are covered in the G-Protein Coupled Receptors (GPCRs) Market?
- Who are the key players in the G-Protein Coupled Receptors (GPCRs) market?
- What is G-Protein Coupled Receptors (GPCRs) ?
- What segments are covered in the G-Protein Coupled Receptors (GPCRs) Market?
- Who are the leading companies and what are their portfolios in G-Protein Coupled Receptors (GPCRs) Market?
Key Offerings:
- Market Size, Share, Size & Forecast by different segment
- Market Dynamics – Growth Drivers, Restraints, Opportunities, and Key Trends by Region
- Market Segmentation – A detailed analysis by segment with their sub-segments and Region
- Competitive Landscape – Profiles of selected key players by region from a strategic perspective
- Competitive landscape – Market Leaders, Market Followers, Regional player
- Competitive benchmarking of key players by region
- PESTLE Analysis
- PORTER’s analysis
- Value chain and supply chain analysis
- Legal Aspects of Business by Region
- Lucrative business opportunities with SWOT analysis
- Recommendations
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