In 2021, the market for Cell Culture worldwide was worth $23 billion US dollars. AMR Group projects that the market will reach US$ 62 billion by 2031, growing at a CAGR of 13 percent between 2022 and 2031.
Industry Overview
Cell Culture is the technique of isolating cells from a plant or an animal and growing them in a controlled in vitro environment. However, this artificial environment has the vital nutrients necessary for cell proliferation and growth, which involves the temperature, gases, pH and humidity. Tissues can be mechanically or enzymatically removed of their cells prior to cultivation. The cells that are need to be grown could also be isolated from an established cell line or cell strain.
The cell culture market has various consumables and equipment’s required at different stages of the cell culture technique to understand the basic biochemistry and biology of cells. It works as a model system and can be used for different applications such as cancer research, stem cell research, bio production, diagnostics, and drug screening. The market is driven by factors such as the growth in biopharmaceutical market, growing demand for monoclonal antibodies, increasing prevalence of chronic diseases, increase in research funding, and rising adoption of single-use technologies. In addition, disposal of plastic waste generated from single-use technologies, cell line misidentification, and cross-contamination hamper the growth of this market to a notable extent. Recent developments in gene expression technologies have provided the production of novel vaccines and biopharmaceuticals, thereby increasing the research & development applications of cell culture techniques.
Market Dynamics
The Cell Culture market tends to grow due to the increasing investment in the R&D by the major market players in development of new cell culture product is anticipated to propel the market growth. In 2021, Pall Corporation, a global supplier of separations, filtration, and purification of products announced that Pall Corporation and Cytiva, had jointly invested US$ 400 million in cell culture media. Also, increasing approvals of strategies like acquisition by major players operating in market is expected to fuel growth of the cell culture market. Cell-based research studies helped to understand the cells’ responses to any chemical and identify novel components that can be used for people’s well-being.
In past years, Cell biology involved extensively in R&D on new therapies of gene therapies and stem cell. The reagents, equipment, and other products related with research and analysis must be of the highest quality and proper condition to provide the most accurate results. The growing need to maintain high-quality standards and comply with guidelines set up by regulatory bodies, the cost of cell biology research has raised considerably. Thus, high cost for the process is a restraining factor in the global cell culture market.
COVID Impact
The COVID-19 pandemic has mildly impacted the Cell Culture Markets major pharmaceutical and biotech companies. As they collaborated to find vaccines and treatment methods during the pandemic as well. The idea behind the collaboration was to make partnerships and evaluate solutions as early as possible during the pandemic period which could not be completely possible with any one organization alone. Joint ventures also took place within universities and companies to speed up the research and production process. Outsourcing of pharmaceutical and biotechnological research to contract research organizations (CROs) also increased during the pandemic. In April 2020, AstraZeneca and Oxford Biomedica plc signed an agreement for the global development and distribution of the University’s potential recombinant adenovirus vaccine, however the development & worldwide manufacturing and distribution of the vaccine was the responsibility of AstraZeneca.
Regional Trend
Geographically, the global Cell Culture market is segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Globally, North America dominates the Cell Culture market due to high research and development investments, the presence of a well-established scientific infrastructure, significant demand for animal component-free media, and other factors. In 2021, North America had the largest revenue share of 40% across the world. Asia Pacific is anticipated to register a higher due to the increasing healthcare expenditure, growing awareness regarding cell & gene therapies, and a huge potential for clinical research applications available in this region. In addition, the surge in adoption of scientific technologies and therapeutics, like cancer immunotherapies and regenerative medicines are likely to strengthen the industry’s growth in the coming future.
Competitive Landscape
Key players operating in the global Cell Culture market are Agilent Technologies, Inc., Avantor, Inc., Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., BioSpherix, Ltd., Bio-Techne Corporation, Corning Incorporated, Cytiva, Eppendorf SE, FUJIFILM Holdings Corporation, Getinge AB, Greiner Bio-One GmbH, HiMedia Laboratories, Lonza Group Ltd., Merck KGaA, Miltenyi Biotec B.V. & Co. KG, PromoCell GmbH, Sartorius AG, Thermo Fisher Scientific, Inc., and VWR International, LLC among others. Recently, in January 2022, BioIVT introduced its GMP Grade Human AB Serum specialized for gene therapy manufacturing. Top companies in the market are Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, Inc., and Becton, Dickinson, & Company can significantly drive the market.
Key USP’s-
In January 2022, Cytiva (Danaher Corporation) collaborated with Nucleus Biologics for the development of custom culture media for cell and gene therapies. Expansion of the existing service offerings is being undertaken by emerging players to increase their market presence.
Market Segmentation
Based upon the Product used in cell culture market is segmented into two major segments Consumables and Equipment in the cell culture process. Further it is categorized according to its process and utilization. Based on application, the cell culture market is segmented into Bioproduction, Drug Screening & Development, Cancer Research and Stem Cell Research. Among the application segments, in 2022, the bioproduction segment is estimated to account for the largest share of the cell culture market. The major factors contributing to the large market share of this segment are the consumption of cell culture products for commercial bioproduction and research. The rising demand for pharma and biopharma products, and the availability of funds used for research activities.
End user segment of cell culture market is further divided into Pharmaceutical & Biotechnology Companies and Academic & Research Institutes. The pharmaceutical & biotechnology companies segment was accounted for the largest share of the cell culture market. Factors driving the large market share of this segment are the high consumption of cell culture products in commercial & research bioproduction and relatively greater purchasing power than other end users.
By Product Type
o Media
o Reagents
o Cells and Cell Lines
o Sera
o Cell Culture Vessels
o Bioreactors
o Biosafety Cabinets
o Incubators
o Cryopreservation Containers
o Refrigerators and Freezers
o Sterilizers
o Microscopes
o Centrifuges
o Cell Counters
o Water Baths
By Application
o Monoclonal Antibody Production
o Therapeutic Protein Production
o Vaccine Production
o Cell and Gene therapy
By End User
Global Cell Culture Market: Regional Analysis
The countries covered in the regional analysis of the Global Cell Culture market report are U.S., Canada, and Mexico in North America, Germany, France, U.K., Russia, Italy, Spain, Turkey, Netherlands, Switzerland, Belgium, and Rest of Europe in Europe, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, China, Japan, India, South Korea, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), and Argentina, Brazil, and Rest of South America as part of South America.
Analysis of the impact of COVID-19 and the Russia-Ukraine War:
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