Overview and Scope
Ligase enzymes refer to a class of proteins that catalyze the joining of two DNA strands. These enzymes are extensively used in biotechnology and pharmaceuticals as they are essential in various cellular processes, including DNA replication and protein synthesis.
Sizing and Forecast
The ligases enzyme market size has grown rapidly in recent years. It will grow from $2.89 billion in 2023 to $3.21 billion in 2024 at a compound annual growth rate (CAGR) of 11.3%. The growth in the historic period can be attributed to initial discovery and development of ligase enzymes, growth of the biotechnology industry, increased understanding of dna repair mechanisms, expansion of genetic engineering applications, rise in demand for molecular diagnostics.
The ligases enzyme market size is expected to see rapid growth in the next few years. It will grow to $4.92 billion in 2028 at a compound annual growth rate (CAGR) of 11.2%. The growth in the forecast period can be attributed to expansion of personalized medicine applications, growing focus on synthetic biology, adoption of ligase enzymes in drug development, increased demand for molecular diagnostics, integration of ligases in next-generation sequencing. Major trends in the forecast period include development of engineered ligases for specific applications, integration of ligase enzymes in crispr-based technologies, customization of ligase-based assays for research and diagnostics, rise of ligase-based isothermal amplification methods, adoption of ligase chain reaction (lcr) in diagnostic assays.
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Segmentation & Regional Insights
The ligases enzyme market covered in this report is segmented –
1) By Type: E. coli DNA ligase, T4 DNA Ligase, Mammalian Ligases, Thermostable Ligases
2) By Source: Microorganisms, Animal, Plant
3) By Application: Ligase Chain Reaction (LCR), Ligase Detection Reaction (LDR), Next-Generation Sequencing (NGS), Repeat Expansion Detection (RED), Rolling Circle Amplification (RCA), Proximity Ligation Assay (PLA), Molecular Cloning, Ligation Mediated PCR, Mutation Detection
4) By End-User: Research Laboratories And Institutions, Pharmaceutical And Biopharmaceutical Companies, Diagnostic Laboratories
North America was the largest region in the ligases enzyme market in 2023. Asia-Pacific is expected to be the fastest-growing region in the ligases enzyme market report during the forecast period. The regions covered in the ligases enzyme market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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Major Driver Impacting Market Growth
The increasing prevalence of cancer and genetic disorders is expected to propel the growth of the ligase’s enzyme market going forward. Cancer refers to a group of diseases characterized by the uncontrolled growth and spread of abnormal cells, and genetic disorders refer to a wide range of medical conditions caused by abnormalities or mutations in an individual’s genetic material, particularly in their DNA. Ligases enzymes are essential for DNA replication, repair, and recombination. In cancer, ligases can be used to repair damaged DNA, leading to the uncontrolled growth of cells. Ligases can also be used to target and kill cells with genetic disorders. For instance, in June 2023, according to the reports shared by the Centers for Disease Control and Prevention, a US-based government agency, in the United States, 1,603,844 new instances of cancer were reported in 2020, and 602,347 cancer-related deaths were recorded. Furthermore, 403 new cancer cases and 144 cancer-related deaths were reported for every 100,000 people. Furthermore, in February 2023, according to Gene People UK, a UK-based registered charity group, around 1 in 25 children are affected by a genetic condition in the UK, leading to more than 2.4 million children and adults in the UK living with a genetic disorder, and 30,000 babies and children are newly diagnosed each year. Therefore, the increasing prevalence of cancer and genetic disorders is driving the growth of the ligase’s enzyme market.
Key Industry Players
Major companies operating in the ligases enzyme market report are BASF SE, F. Hoffmann-La Roche AG, Thermo Fisher Scientific Inc., Merck KGaA, Becton Dickinson And Company (BD), Agilent Technologies Inc., Illumina Inc., QIAGEN N.V., Novo Holdings AS, GenScript, VWR International, R And D Systems Inc., Promega Corporation, Oxford Nanopore Technologies Limited, Takara Bio Inc., New England Biolabs Inc., BioVision Inc., Enzo Life Sciences, Zymo Research, LGC Biosearch Technologies, Genetix Biotech Asia Pvt. Ltd., BLIRT S.A., Jena Bioscience, Bioline, Creative Enzymes, ArcticZymes Technologies ASA
The ligases enzyme market report table of contents includes:
1. Executive Summary
2. Ligases Enzyme Market Characteristics
3. Ligases Enzyme Market Trends And Strategies
4. Ligases Enzyme Market – Macro Economic Scenario
5. Global Ligases Enzyme Market Size and Growth
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32. Global Ligases Enzyme Market Competitive Benchmarking
33. Global Ligases Enzyme Market Competitive Dashboard
34. Key Mergers And Acquisitions In The Ligases Enzyme Market
35. Ligases Enzyme Market Future Outlook and Potential Analysis
36. Appendix
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