The U.K. pharmacovigilance market size was valued at USD 211.05 million in 2020 and is expected to expand at a compound annual growth rate (CAGR) of 11.9% from 2021 to 2028. Rising incidence of Adverse Drug Reactions (ADRs) owing to drug abuse and the prevalence of diseases that require a combination of drugs are major growth drivers of the overall market. In addition, an upward shift in the production of new drugs and the presence of a stringent government regulatory framework for drug safety are responsible for the significant growth of the market.
The U.K. has left the European Union and the Brexit transition period came to an end in December 2020. By the end of this period, the legal framework changed, disturbing all involved parties. Starting from January 2021, the U.K. will only have one main medication regulator-the Medicines and Healthcare products Regulatory Agency (MHRA), which will retain full accountability for pharmacovigilance. In November 2020, the MHRA delivered several documents that serve as guidelines to help affected parties, particularly Marketing Authorization Holders (MAH) in the whole country, to acclimate to the future scenario.
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The pandemic is changing the way the industry is handling ongoing or upcoming clinical trials. The pandemic has accelerated the need for remote and risk-based monitoring in clinical research, which, in turn, has augmented the acceptance of virtual trial technology. This technology was deployed to speed vaccine development and helped secure full-service COVID trials and new studies. The U.K. government has adopted progressive technologies to support the processing of adverse event reports relating to COVID-19 vaccines, paying Genpact U.K. USD 2.08 million (£1.5) to develop a powerful, vaccine-specific AI tool to sift through adverse drug reactions.
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Advancements in the development of ADR databases and information systems have enabled reporting accurate information, which can be further utilized by research professionals for prospective clinical studies, thereby fueling the overall demand for the market. Moreover, increasing drug development activities in areas, such as personalized medicines, biosimilars, orphan drugs, companion diagnostics, along with adaptive trial designs, are projected to boost the demand for pharmacovigilance (PV) services in the coming years. According to the Royal Society of Chemistry Position Paper, U.K. had been a world spearhead in medicines discovery and research with as a minimum 10 of the top-selling drugs globally having U.K.-trained PhD organic chemists as named originators.
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